Perspectives from 16 years of working at the intersection of biomedical science and commercial strategy. No thought leadership for its own sake — only what's actually useful.
Commercialization
The failure modes in health innovation are remarkably consistent. This piece examines the five commercial gaps that appear most frequently in C.H.I.E.F.S. evaluations — and why they're almost always preventable.
Health-Economics
The gap between clinical proof and procurement-ready economics is where most health innovations stall. A practical guide to building the economic case payers actually need.
IP Strategy
The IP gaps that kill deals most often aren't the ones founders worry about. A guide to the freedom-to-operate, know-how, and claim-scope issues that surface in diligence.
Fundraising
How the Financials pillar of C.H.I.E.F.S. exposes the most common capital strategy error — and why sophisticated investors always notice.
Institutional Buyers
The decision-maker mapping problem that shows up in the Customer pillar of nearly every evaluation. A guide to finding the real buyer.
Exit Strategy
What the Exit Strategy factor in C.H.I.E.F.S. actually tests for — and the three questions your exit thesis needs to answer before investors will take it seriously.
Commercialization
What it means when hospital pilots end without paid contracts — and the specific commercial gaps that typically explain the stall.
Framework
The reasoning behind the pillar sequence and why the most common mistake in health innovation is building the commercial case in the wrong order.
IP Strategy
Filed patents are a starting point. The 13 IP criteria in C.H.I.E.F.S. test for something harder — and something acquirers care about far more.
By Topic
Every C.H.I.E.F.S. pillar has its own body of insight. Explore by the area that matters most to you right now.
C · Pillar 01
Decision-maker mapping, channel strategy, TAM/SAM/SOM, and the buyer personas that actually sign.
6 articles →H · Pillar 02
Building cost-displacement models, reimbursement strategy, and the economics case payers need.
8 articles →I · Pillar 03
IP defensibility, freedom-to-operate, clinical evidence standards, and development maturity.
7 articles →E · Pillar 04
Team composition, milestone discipline, regulatory pathway management, and partnership traction.
5 articles →F · Pillar 05
Capital sequencing, use of funds, dilutive vs non-dilutive strategy, and investor-ready financials.
6 articles →S · Pillar 06
Corporate development readiness, acquirer mapping, exit thesis construction, and strategic partnerships.
5 articles →Stay Current
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